Central Nervous System Disposition and Metabolism of Fosdevirine (GSK2248761), a Non-Nucleoside Reverse Transcriptase Inhibitor: An LC-MS and Matrix-Assisted Laser Desorption/Ionization Imaging MS Investigation into Central Nervous System Toxicity-Reference-Cited by-同舟云学术

Central Nervous System Disposition and Metabolism of Fosdevirine (GSK2248761), a Non-Nucleoside Reverse Transcriptase Inhibitor: An LC-MS and Matrix-Assisted Laser Desorption/Ionization Imaging MS Investigation into Central Nervous System Toxicity

Published:2012-12-20 Issue:2 Volume:26 Page:241-251
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Castellino Stephen¹,Groseclose M. Reid¹,Sigafoos James¹,Wagner David¹,de Serres Mark¹,Polli Joseph W.¹,Romach Elizabeth²,Myer James²,Hamilton Brad²

Affiliation:

1. Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, United States

2. Safety Assessment, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx3004196

Reference33 articles.

1. Synthesis and Biological Evaluation of Aryl-phospho-indole as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

2. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)

3. HIV/AIDS: Recent Advances in Antiretroviral Agents

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