A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells-Reference-Cited by-同舟云学术

A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells

Published:2012-11 Issue:12 Volume:3 Page:1034-1038
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Weïwer Michel¹,Spoonamore James¹,Wei Jingqiang¹,Guichard Boris¹,Ross Nathan T.¹,Masson Kristina¹,Silkworth Whitney¹,Dandapani Sivaraman¹,Palmer Michelle¹,Scherer Christina A.¹,Stern Andrew M.¹,Schreiber Stuart L.¹²,Munoz Benito¹

Affiliation:

1. Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

2. Howard Hughes Medical Institute, Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

Funder

Howard Hughes Medical Institute

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml300246r

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1. An Unidentified Virus which causes the Rapid Production of Tumours in Mice

2. ras GENES

3. RAS oncogenes: the first 30 years

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