A Formal Total Synthesis of (−)-FR901483, Using a Tandem Cationic Aza-Cope Rearrangement/Mannich Cyclization Approach
Author:
Affiliation:
1. Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo0483567
Reference22 articles.
1. FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231. Taxonomy of the Producing Organism, Fermentation, Isolation,Physico-chemical Properties and Biological Activities.
2. Total Synthesis of (−)-FR901483
3. Strained bridgehead double bonds
4. Optically active N-protected .alpha.-amino aldehydes in organic synthesis
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