Limits of RNA 2′-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2′-FRNA:DNA Hybrid-Reference-Cited by-同舟云学术

Limits of RNA 2′-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2′-FRNA:DNA Hybrid

Published:2016-09-14 Issue:38 Volume:55 Page:5321-5325
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Pallan Pradeep S.¹,Prakash Thazha P.²,de Leon Arnie R.¹,Egli Martin¹

Affiliation:

1. Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232, United States

2. Department of Medicinal Chemistry, Ionis Pharmaceuticals Inc., Carlsbad, California 92010, United States

Funder

Vanderbilt University

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.6b00849

Reference27 articles.

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2. Hostomsky, Z., Hostomska, Z., and Matthews, D. A. (1993) inNucleases(Linn, S. M., Lloyd, S. R., and Roberts, R. J., Eds.)2nd ed., pp341–376,Cold Spring Harbor Laboratory Press,Plainview, NY.

3. Molecular diversities of RNases H

4. Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity

5. Ribonuclease H: the enzymes in eukaryotes

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