ALAD Inhibition by Porphobilinogen Rationalizes the Accumulation of δ-Aminolevulinate in Acute Porphyrias-Reference-Cited by-同舟云学术

ALAD Inhibition by Porphobilinogen Rationalizes the Accumulation of δ-Aminolevulinate in Acute Porphyrias

Published:2022-10-14 Issue:21 Volume:61 Page:2409-2416
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

San Juan Itxaso¹,Pereira-Ortuzar Tania¹,Cendoya Xabier²,Laín Ana¹,To-Figueras Jordi³,Mateos Borja¹,Planes Francisco J.²⁴,Bernardo-Seisdedos Ganeko¹⁵,Mato José M.¹⁶,Millet Oscar¹⁵⁶^ORCID

Affiliation:

1. Precision Medicine and Metabolism Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Bizkaia Science and Technology Park, 48160 Derio, Spain

2. , Universidad de Navarra, Tecnun Escuela de Ingeniería y Centro de Ingeniería Biomédica, San Sebastián 20009, Spain

3. Biochemistry and Molecular Genetics Unit, Hospital Clinic, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain

4. Universidad de Navarra, DATAI Instituto de Ciencia de los Datos e Inteligencia Artificial, Pamplona 31009, Spain

5. ATLAS Molecular Pharma, Bizkaia Science and Technology Park, 48160 Derio, Spain

6. Biomedical Research Network on Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, Madrid 28029, Spain

Funder

Agencia Estatal de Investigaci?n

Eusko Jaurlaritza

Horizon 2020 Framework Programme

National Institutes of Health

European Federation of Pharmaceutical Industries and Associations

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00434

Reference26 articles.

1. The porphyrias: advances in diagnosis and treatment

2. The incidence of inherited porphyrias in Europe

3. Update review of the acute porphyrias

4. Estimation and Application of Biological Variation of Urinary δ-Aminolevulinic Acid and Porphobilinogen in Healthy Individuals and in Patients with Acute Intermittent Porphyria

5. Penetrance and predictive value of genetic screening in acute porphyria

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