Differential Effects of Aromatic Residues on Amyloid Formation and Cytotoxicity of Human IAPP-Reference-Cited by-同舟云学术

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Differential Effects of Aromatic Residues on Amyloid Formation and Cytotoxicity of Human IAPP

Published:2022-10-10 Issue:21 Volume:61 Page:2334-2343
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Manathunga Lakshan¹²,Zhyvoloup Alexander³,Baghai Aria³,Raleigh Daniel P.¹³²^ORCID

Affiliation:

1. Department of Chemistry, Stony Brook University, Nicolls Road, Stony Brook, New York 11790, United States

2. Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794, United States

3. Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, U.K.

Funder

Wellcome Trust

Stony Brook University

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00267

Reference60 articles.

1. Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

2. Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

3. The role of amylin in the control of energy homeostasis

4. Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin

5. Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Deciphering the impact of F23L mutation on the aggregation propensity of human islet amyloid polypeptide using molecular simulations;Journal of Molecular Liquids;2024-10

2. Delineating the impact of N21D mutation on the conformational preferences and structural transitions in human islet amyloid polypeptide;Journal of Molecular Liquids;2024-05

3. Structural basis and functional significance of food-derived inhibitors of islet amyloid polypeptide fibrillation toward antidiabetic effects;Current Opinion in Food Science;2024-04

4. Exploring the Curvature-Dependence of Boron Nitride Nanoparticles on the Inhibition of hIAPP Aggregation;The Journal of Physical Chemistry B;2023-08-24

5. Analysis of Sheep and Goat IAPP Provides Insight into IAPP Amyloidogenicity and Cytotoxicity;Biochemistry;2022-10-26

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