Analysis of Sheep and Goat IAPP Provides Insight into IAPP Amyloidogenicity and Cytotoxicity-Reference-Cited by-同舟云学术

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Analysis of Sheep and Goat IAPP Provides Insight into IAPP Amyloidogenicity and Cytotoxicity

Published:2022-10-26 Issue:22 Volume:61 Page:2531-2545
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Miller Matthew E. T.¹^ORCID,Li Ming-Hao²,Baghai Aria³,Peetz Vincent H.¹,Zhyvoloup Alexander³,Raleigh Daniel P.¹³⁴^ORCID

Affiliation:

1. Department of Chemistry, Stony Brook University, Nicolls Road, Stony Brook, New York 11790, United States

2. Graduate Program in Biochemistry and Structural Biology, Stony Brook University, Stony Brook, New York 11790, United States

3. Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom

4. Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, New York 11794, United States

Funder

Wellcome Trust

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.2c00470

Reference62 articles.

1. Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

2. Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

3. Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics

4. The β-cell assassin: IAPP cytotoxicity

5. Protofibrillar Islet Amyloid Polypeptide Permeabilizes Synthetic Vesicles by a Pore-like Mechanism that May Be Relevant to Type II Diabetes

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1. Deciphering the impact of F23L mutation on the aggregation propensity of human islet amyloid polypeptide using molecular simulations;Journal of Molecular Liquids;2024-10

2. Understanding the structural dynamics of human islet amyloid polypeptide: Advancements in and applications of ion-mobility mass spectrometry;Biophysical Chemistry;2024-09

3. Delineating the impact of N21D mutation on the conformational preferences and structural transitions in human islet amyloid polypeptide;Journal of Molecular Liquids;2024-05

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