Tales of Dihydrofolate Binding to R67 Dihydrofolate Reductase-Reference-Cited by-同舟云学术

Tales of Dihydrofolate Binding to R67 Dihydrofolate Reductase

Published:2015-12-21 Issue:1 Volume:55 Page:133-145
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Duff Michael R.¹,Chopra Shaileja¹,Strader Michael Brad²,Agarwal Pratul K.¹³,Howell Elizabeth E.¹

Affiliation:

1. Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996-0840, United States

2. Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993, United States

3. Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States

Funder

Division of Molecular and Cellular Biosciences

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.biochem.5b00981

Reference65 articles.

1. Searching Sequence Space: Two Different Approaches to Dihydrofolate Reductase Catalysis

2. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site

3. Unusual Binding Stoichiometries and Cooperativity Are Observed during Binary and Ternary Complex Formation in the Single Active Pore of R67 Dihydrofolate Reductase, a D2 Symmetric Protein

4. Interligand Overhauser Effects in Type II Dihydrofolate Reductase

5. Crystal Structure of a Type II Dihydrofolate Reductase Catalytic Ternary Complex

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. From a binding module to essential catalytic activity: how nature stumbled on a good thing;Chemical Communications;2023

2. Temperature-Dependent Kinetic Isotope Effects in R67 Dihydrofolate Reductase from Path-Integral Simulations;The Journal of Physical Chemistry B;2021-02-01

3. Dual-Target Inhibitors of the Folate Pathway Inhibit Intrinsically Trimethoprim-Resistant DfrB Dihydrofolate Reductases;ACS Medicinal Chemistry Letters;2020-09-28

4. Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues;ACS Omega;2019-06-10

5. Small Angle Neutron Scattering Studies of R67 Dihydrofolate Reductase, a Tetrameric Protein with Intrinsically Disordered N-Termini;Biochemistry;2017-10-11