Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode
Author:
Affiliation:
1. Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, United States
Funder
National Institute of Allergy and Infectious Diseases
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.1c00414
Reference33 articles.
1. Human viruses: discovery and emergence
2. Epidemiological dynamics of enterovirus D68 in the United States and implications for acute flaccid myelitis
3. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
4. Discovery and Selection of TMC114, a Next Generation HIV-1 Protease Inhibitor
5. HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK
Cited by 26 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. From docking to dynamics: Unveiling the potential non-peptide and non-covalent inhibitors of Mpro from natural products;Computers in Biology and Medicine;2024-10
2. Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance;Viruses;2024-09-05
3. Crystal structures of the 3C proteases from Coxsackievirus B3 and B4;Acta Crystallographica Section F Structural Biology Communications;2024-07-25
4. Crystallographic fragment screen of Enterovirus D68 3C protease and iterative design of lead-like compounds using structure-guided expansions;2024-05-01
5. An isothermal calorimetry assay for determining steady state kinetic and enzyme inhibition parameters for SARS-CoV-2 3CL-protease;2024-01-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3