Drugging the Undruggable: How Isoquinolines and PKA Initiated the Era of Designed Protein Kinase Inhibitor Therapeutics-Reference-Cited by-同舟云学术

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Drugging the Undruggable: How Isoquinolines and PKA Initiated the Era of Designed Protein Kinase Inhibitor Therapeutics

Published:2021-08-09 Issue:46 Volume:60 Page:3470-3484
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Lorenz Robin¹^ORCID,Wu Jian²^ORCID,Herberg Friedrich W.¹^ORCID,Taylor Susan S.²³^ORCID,Engh Richard A.⁴^ORCID

Affiliation:

1. Department of Biochemistry, Institute for Biology, University of Kassel, Kassel 34132, Germany

2. Department of Pharmacology, University of California, San Diego, 9400 Gilman Drive, La Jolla, California 92093-0654, United States

3. Department of Chemistry and Biochemistry, University of California, San Diego, 9400 Gilman Drive, La Jolla, California 92093-0654, United States

4. The Norwegian Structural Biology Centre, Department of Chemistry, UiT the Arctic University of Norway, Tromsø 9012, Norway

Funder

Bundesministerium f??r Bildung und Forschung

Deutsche Forschungsgemeinschaft

National Institute of General Medical Sciences

Universit??t Kassel

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.1c00359

Reference138 articles.

1. Kinase mutations in human disease: interpreting genotype–phenotype relationships

2. Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors

3. New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome

4. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

5. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

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