Design of an Activity-Based Probe for Human Neutrophil Elastase: Implementation of the Lossen Rearrangement To Induce Förster Resonance Energy Transfers

Author:

Schulz-Fincke Anna-Christina1,Tikhomirov Alexander S.12,Braune Annett3,Girbl Tamara4,Gilberg Erik15,Bajorath Jürgen5ORCID,Blaut Michael3,Nourshargh Sussan4,Gütschow Michael1ORCID

Affiliation:

1. Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany

2. Gause Institute of New Antibiotics, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia

3. Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114−116, 14558 Nuthetal, Germany

4. William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U.K.

5. Department of Life Science Informatics, B-IT, LIMES Program Unit of Chemical Biology and Medicinal Chemistry, University of Bonn, Dahlmannstrasse 2, 53113 Bonn, Germany

Funder

Deutscher Akademischer Austauschdienst

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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