The Cardiomyopathy Mutation, R146G Troponin I, Stabilizes the Intermediate “C” State of Regulated Actin under High- and Low-Free Ca2+ Conditions-Reference-Cited by-同舟云学术

The Cardiomyopathy Mutation, R146G Troponin I, Stabilizes the Intermediate “C” State of Regulated Actin under High- and Low-Free Ca2+ Conditions

Published:2016-08-03 Issue:32 Volume:55 Page:4533-4540
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Johnson Dylan¹²,Mathur Mohit C.¹,Kobayashi Tomoyoshi³,Chalovich Joseph M.¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, United States

2. Department of Chemistry, East Carolina University, Greenville, North Carolina 27858-4353, United States

3. Department of Physiology and Biophysics and Center for Cardiovascular Research, College of Medicine, University of Illinois, Chicago, Illinois 60612-7342, United States

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.5b01359

Reference57 articles.

1. A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction.

2. Structures of the troponin C regulatory domains in the apo and calcium-saturated states

3. Actin mediated regulation of muscle contraction