Why Are Lopinavir and Ritonavir Effective against the Newly Emerged Coronavirus 2019? Atomistic Insights into the Inhibitory Mechanisms

Author:

Nutho Bodee1,Mahalapbutr Panupong2,Hengphasatporn Kowit3,Pattaranggoon Nawanwat Chainuwong4,Simanon Nattapon4,Shigeta Yasuteru3ORCID,Hannongbua Supot1,Rungrotmongkol Thanyada24ORCID

Affiliation:

1. Center of Excellence in Computational Chemistry (CECC), Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand

2. Structural and Computational Biology Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand

3. Center for Computational Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

4. Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand

Funder

Chulalongkorn University

National Science and Technology Development Agency

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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