One-Step Conjugation Method for Site-Specific Antibody–Drug Conjugates through Reactive Cysteine-Engineered Antibodies-Reference-Cited by-同舟云学术

One-Step Conjugation Method for Site-Specific Antibody–Drug Conjugates through Reactive Cysteine-Engineered Antibodies

Published:2016-04-28 Issue:5 Volume:27 Page:1324-1331
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Shinmi Daisuke¹,Taguchi Eri¹,Iwano Junko¹,Yamaguchi Tsuyoshi¹,Masuda Kazuhiro¹,Enokizono Junichi¹,Shiraishi Yasuhisa¹

Affiliation:

1. Research Core Function Laboratories and §Innovative Technology Laboratories, Research Functions Unit, #R&D Planning Department, R&D Division, and ‡Bio Process Research and Development Laboratories, Production Division, Kyowa Hakko Kirin Co., Ltd., Tokyo, 100-8185, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.6b00133

Reference32 articles.

1. Maturing antibody–drug conjugate pipeline hits 30

2. Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

3. Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

4. Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development

5. Design and Application of Antibody Cysteine Variants

Cited by 54 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antibody-Drug Conjugate Overview: a State-of-the-art Manufacturing Process and Control Strategy;Pharmaceutical Research;2024-02-17

2. Chemical technology principles for selective bioconjugation of proteins and antibodies;Chemical Society Reviews;2024

3. Site-Specific Antibody Conjugation Using Modified Bisected N-Glycans: Method Development and Potential toward Tunable Effector Function;Bioconjugate Chemistry;2023-08-24

4. Light Chain Q166C Mutation Permits One‐step Site Specific Conjugation on Monoclonal Antibodies;ChemBioChem;2023-06

5. Technology Advancement in Development of Antibody Drug Conjugates;PROG BIOCHEM BIOPHYS;2023