Site-Specific Antibody Conjugation Using Modified Bisected <i>N</i>-Glycans: Method Development and Potential toward Tunable Effector Function-Reference-Cited by-同舟云学术

Site-Specific Antibody Conjugation Using Modified Bisected N-Glycans: Method Development and Potential toward Tunable Effector Function

Published:2023-08-24 Issue:9 Volume:34 Page:1633-1644
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Hsu Yen-Pang¹^ORCID,Nourzaie Omar²,Tocher Ariel E.³,Nerella Kavitha¹,Ermakov Grigori²,Jung Jiwon²,Fowler Alexandra¹,Wu Peidong¹,Ayesa Umme⁴,Willingham Aarron²,Beaumont Maribel²,Ingale Sampat¹^ORCID

Affiliation:

1. MRL, Merck & Co., Inc., 320 Bent St., Cambridge, Massachusetts 02141, United States

2. MRL, Merck & Co., Inc., 213 E. Grand Ave., South San Francisco, California 94080, United States

3. MRL, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States

4. MRL, Merck & Co., Inc., 90 E. Scott Ave., Rahway, New Jersey 07065, United States

Funder

Merck Sharp and Dohme

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.3c00302

Reference72 articles.

1. An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy

2. Antibody Conjugates-Recent Advances and Future Innovations

3. Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

4. Pushing the Envelope: Advancement of ADCs Outside of Oncology

5. Lysosome-targeting chimaeras for degradation of extracellular proteins

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