Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability-Reference-Cited by-同舟云学术

Dimerization of the Peptide CXCR4-Antagonist on Macromolecular and Supramolecular Protraction Arms Affords Increased Potency and Enhanced Plasma Stability

Published:2022-03-16 Issue:4 Volume:33 Page:594-607
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Harms Mirja¹,Hansson Rikke Fabech²^ORCID,Carmali Sheiliza²,Almeida-Hernández Yasser³,Sanchez-Garcia Elsa³^ORCID,Münch Jan¹^ORCID,Zelikin Alexander N.²^ORCID

Affiliation:

1. Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany

2. Department of Chemistry and iNano Interdisciplinary Nanoscience Centre, Aarhus University, Aarhus 8000, Denmark

3. Computational Biochemistry, Center of Medical Biotechnology, University Duisburg-Essen, D-45141 Essen, Germany

Funder

Deutsche Forschungsgemeinschaft

Baden-W?rttemberg Stiftung

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.2c00034

Reference72 articles.

1. Advances in therapeutic peptides targeting G protein-coupled receptors

2. Advances in oral peptide therapeutics

3. Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

4. Molecular, Macromolecular, and Supramolecular Glucuronide Prodrugs: Lead Identified for Anticancer Prodrug Monotherapy

5. Chemically Defined Antibody– and Small Molecule–Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis

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