Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo-Reference-Cited by-同舟云学术

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

Published:2018-06-13 Issue:7 Volume:29 Page:2478-2488
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Sharma Vivek K.,Osborn Maire F.^ORCID,Hassler Matthew R.,Echeverria Dimas,Ly Socheata,Ulashchik Egor A.¹,Martynenko-Makaev Yury V.¹,Shmanai Vadim V.¹,Zatsepin Timofei S.²³^ORCID,Khvorova Anastasia,Watts Jonathan K.^ORCID

Affiliation:

1. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Surganova 13, 220072 Minsk, Belarus

2. Center for Translational Biomedicine, Skolkovo Institute of Science and Technology, Skolkovo, 143026 Moscow, Russia

3. Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 1-3, 119992 Moscow, Russia

Funder

National Institute of Neurological Disorders and Stroke

NIH Office of the Director

University of Massachusetts Medical School

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.8b00365

Reference62 articles.

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5. Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor

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