Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes-Reference-Cited by-同舟云学术

Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes

Published:2022-07-23 Issue:8 Volume:33 Page:1494-1504
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Wade Jack¹^ORCID,Rimbault Charlotte¹^ORCID,Ali Hanif²,Ledsgaard Line¹,Rivera-de-Torre Esperanza¹,Abou Hachem Maher¹^ORCID,Boddum Kim³,Mirza Nadia⁴,Bohn Markus-Frederik¹,Sakya Siri A.⁵⁶,Ruso-Julve Fulgencio⁵⁶^ORCID,Andersen Jan Terje⁵⁶^ORCID,Laustsen Andreas H.¹^ORCID

Affiliation:

1. Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800 Kongens, Lyngby, Denmark

2. Quadrucept Bio Ltd., Kemp House, 152 City Road, London EC1V 2NX, United Kingdom

3. Sophion Bioscience, DK-2750 Ballerup, Denmark

4. Fida Biosystems ApS, DK-2860 Søborg, Copenhagen, Denmark

5. Department of Immunology, Oslo University Hospital Rikshospitalet, N-0372 Oslo, Norway

6. Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, N-0372 Oslo, Norway

Funder

Norges Forskningsr?d

Villum Fonden

Carlsbergfondet

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.2c00220

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