Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of αvβ3 Integrin Expression with Gallium-68

Author:

Imberti Cinzia1,Terry Samantha Y. A.1,Cullinane Carleen23,Clarke Fiona4,Cornish Georgina H.4,Ramakrishnan Nisha K.1,Roselt Peter2,Cope Andrew P.4,Hicks Rodney J.23,Blower Philip J.1,Ma Michelle T.1ORCID

Affiliation:

1. King’s College London, Division of Imaging Sciences and Biomedical Engineering, Fourth Floor Lambeth Wing, St Thomas’ Hospital, London SE1 7EH, United Kingdom

2. Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia

3. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia

4. King’s College London, Academic Department of Rheumatology, Centre for Molecular and Cellular Biology of Inflammation, Faculty of Life Sciences and Medicine, London SE1 1UL, United Kingdom

Funder

Engineering and Physical Sciences Research Council

Medical Research Council

Department of Health

Arthritis Research UK

Royal Society of Chemistry

Wellcome Trust

Directorate-General for Research and Innovation

Kings College London

Cancer Research UK

NHS Foundation Trust

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

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