One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1-Reference-Cited by-同舟云学术

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1

Published:2018-09-19 Issue:10 Volume:29 Page:3245-3249
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Harmand Thibault J.¹^ORCID,Bousbaine Djenet¹²,Chan Alix³^ORCID,Zhang Xiaohong⁴,Liu David R.³,Tam James P.⁴^ORCID,Ploegh Hidde L.¹^ORCID

Affiliation:

1. Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachussets 02115, United States

2. Department of Microbiology, Massachusetts Institute of Technology, Cambridge, Massachussets 02139, United States

3. The Broad Institute of Harvard and MIT, Howard Hughes Medical Institute, and the Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachussets 02142, United States

4. School of Biological Sciences, Nanyang Technological University, 637551, Singapore

Funder

Howard Hughes Medical Institute

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Ministry of Education - Singapore

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.bioconjchem.8b00563

Reference30 articles.

1. Advances in Chemical Protein Modification

2. Investigation into Temperature-Induced Aggregation of an Antibody Drug Conjugate

3. Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

4. Protein conjugation with genetically encoded unnatural amino acids

5. A General and Efficient Method for the Site-Specific Dual-Labeling of Proteins for Single Molecule Fluorescence Resonance Energy Transfer

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