Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces-Reference-Cited by-同舟云学术

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Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces

Published:2024-03-18 Issue:1 Volume:16 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

van der Wulp W.¹²^ORCID,Luu W.³,Ressing M. E.¹,Schuurman J.³,van Kasteren S. I.⁴,Guelen L.³,Hoeben R. C.¹,Bleijlevens B.³,Heemskerk M. H. M.²

Affiliation:

1. Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands

2. Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands

3. Genmab, Utrecht, The Netherlands

4. Division of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Funder

Genma

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2024.2329321

Reference24 articles.

1. Sensitization of Tumors for Attack by Virus-Specific CD8+ T-Cells Through Antibody-Mediated Delivery of Immunogenic T-Cell Epitopes

2. Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy

3. Single-cell imaging of T cell immunotherapy responses in vivo

4. Antibody-mediated delivery of a viral MHC-I epitope into the cytosol of target tumor cells repurposes virus-specific CD8+ T cells for cancer immunotherapy

5. Antibody-peptide epitope conjugates for personalized cancer therapy

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