Asymmetric and Highly Stereoselective Synthesis of the DEF-Ring Moiety of (−)-FR182877 and Its Derivative Inducing Mitotic Arrest
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol300615w
Reference28 articles.
1. A New Antimitotic Substance, FR182877. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities.
2. A New Antimitotic Substance, FR182877. II. The Mechanism of Action.
3. A New Antimitotic Substance, FR182877. III. Structure Determination.
4. Isolation of a Novel Cyclic Hexadepsipeptide Pipalamycin from Streptomyces as an Apoptosis-inducing Agent.
5. FR182876, a New Microtubule Modulator with High Water-solubility, from a Streptomyces
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