Dramatic influence of ester steric hindrance on the diastereoselectivity of a Michael addition towards the synthesis of the ABC tricycle of hexacyclinic acid
Author:
Funder
Ecole Polytechnique, the University of Glasgow
EPSRC
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference16 articles.
1. Hexacyclinic acid, a Polyketide fromStreptomyces with a Novel Carbon Skeleton
2. Asymmetric and Highly Stereoselective Synthesis of the DEF-Ring Moiety of (−)-FR182877 and Its Derivative Inducing Mitotic Arrest
3. Synthesis of a model DEF-ring core of hexacyclinic acidElectronic supplementary information (ESI) available: experimental procedures and characterisation data. See http://www.rsc.org/suppdata/cc/b3/b303706a/
4. Synthetic studies on the DEF-rings of FR182877 and hexacyclinic acid
5. Studies on transannulation reactions across a nine-membered ring: the synthesis of natural product-like structures
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1. Synthesis of the CDF Ring System of Hexacyclinic Acid;Synthesis;2023-01-30
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