Solid-Phase Synthesis and Insights into Structure−Activity Relationships of Safinamide Analogues as Potent and Selective Inhibitors of Type B Monoamine Oxidase-Reference-Cited by-同舟云学术

Solid-Phase Synthesis and Insights into Structure−Activity Relationships of Safinamide Analogues as Potent and Selective Inhibitors of Type B Monoamine Oxidase

Published:2007-09-07 Issue:20 Volume:50 Page:4909-4916
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Leonetti Francesco¹,Capaldi Carmelida¹,Pisani Leonardo¹,Nicolotti Orazio¹,Muncipinto Giovanni¹,Stefanachi Angela¹,Cellamare Saverio¹,Caccia Carla¹,Carotti Angelo¹

Affiliation:

1. Dipartimento Farmaco-Chimico, University of Bari, Via Orabona 4, I-70125 Bari, Italy, and Newron Pharmaceuticals, Via L. Ariosto 21, Bresso, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070725e

Reference39 articles.

1. Enzymology of monoamine oxidase

2. Clinical Pharmacology of MAO Inhibitors: Safety and Future

3. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

4. Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

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