Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway-Reference-Cited by-同舟云学术

Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway

Published:2022-12-07 Issue:1 Volume:6 Page:76-87
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Wang Fengqin¹,Zhan Ying¹,Li Manman¹,Wang Lidan¹²,Zheng Austin³,Liu Changbai¹,Wang Hu¹³^ORCID,Wang Tao⁴

Affiliation:

1. Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang 443002, China

2. Department of Microbiology and Immunology, Medical School, China Three Gorges University, Yichang 443002, China

3. Institute of Cell Engineering, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21215, United States

4. The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, Hubei 443003, China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00165

Reference69 articles.

1. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis

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3. Hepatic Fibrosis Inhibitory Effect of Peptides Isolated from Navicula incerta on TGF-β Induced Activation of LX-2 Human Hepatic Stellate Cells

4. Mechanisms of liver fibrosis resolution

5. Liver fibrosis markers in alcoholic liver disease

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