Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds-Reference-Cited by-同舟云学术

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Development of Melanocortin 4 Receptor Agonists by Exploiting Animal-Derived Macrocyclic, Disulfide-Rich Peptide Scaffolds

Published:2023-09-26 Issue:10 Volume:6 Page:1373-1381
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Muratspahić Edin¹²,Aslanoglou Despoina³,White Andrew M.²^ORCID,Draxler Claudia¹,Kozisek Xaver¹,Farooq Zara³,Craik David J.²^ORCID,McCormick Peter J.³,Durek Thomas²,Gruber Christian W.¹^ORCID

Affiliation:

1. Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, 1090 Vienna, Austria

2. Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia

3. Department of Endocrinology, Queen Mary University of London, London E1 4NS, U.K.

Funder

Bundesministerium für Bildung und Forschung

Austrian Science Fund

National Health and Medical Research Council

Australian Research Council

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.3c00090

Reference33 articles.

1. Structure, function and regulation of the melanocortin receptors

2. Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment

3. Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

4. Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

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1. Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor;Journal of Biological Chemistry;2024-06

2. Novel BRICHOS-Related Antimicrobial Peptides from the Marine Worm Heteromastus filiformis: Transcriptome Mining, Synthesis, Biological Activities, and Therapeutic Potential;Marine Drugs;2023-12-14

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