Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination-Reference-Cited by-同舟云学术

Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination

Published:2018-07-26 Issue:1 Volume:1 Page:12-20
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Liang Yi-Lynn¹,Zhao Peishen¹,Draper-Joyce Christopher¹,Baltos Jo-Anne¹,Glukhova Alisa¹,Truong Tin T.¹,May Lauren T.¹,Christopoulos Arthur¹,Wootten Denise¹²,Sexton Patrick M.¹²^ORCID,Furness Sebastian G. B.¹

Affiliation:

1. Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, 3052, Australia

2. School of Pharmacy, Fudan University, Shanghai 201203, China

Funder

National Health and Medical Research Council

Ramaciotti Centre for Cryo-Electron Microscopy, Monash University

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.8b00017

Reference22 articles.

1. Recent advances in the determination of G protein-coupled receptor structures

2. Theoretical Aspects of GPCR–Ligand Complex Pharmacology

3. Crystal structure of the β2 adrenergic receptor–Gs protein complex

4. Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

5. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

Cited by 104 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site;Nature Communications;2024-09-05

2. Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling;PLOS Biology;2024-07-31

3. Growth factor–dependent phosphorylation of Gα _i shapes canonical signaling by G protein–coupled receptors;Science Signaling;2024-06-04

4. Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors;Cell Discovery;2024-05-07

5. Molecular Determinant Underlying Selective Coupling of Primary G‐Protein by Class A GPCRs;Advanced Science;2024-04-22