Lengthening the Guanidine–Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription-Reference-Cited by-同舟云学术

Lengthening the Guanidine–Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription

Published:2022-09-14 Issue:38 Volume:7 Page:34632-34646
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Kohoutova Klara¹²,Dočekal Vojtěch³^ORCID,Ausserlechner Michael J.⁴,Kaiser Nora⁴,Tekel Andrej¹,Mandal Raju¹,Horvath Matej¹,Obsilova Veronika²^ORCID,Vesely Jan³,Hagenbuchner Judith⁵,Obsil Tomas¹²^ORCID

Affiliation:

1. Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Albertov 6, Prague 12843, Czech Republic

2. Institute of Physiology of the Czech Academy of Sciences, Laboratory of Structural Biology of Signaling Proteins, Division BIOCEV, Prumyslova 595, Vestec 25250, Czech Republic

3. Department of Organic Chemistry, Faculty of Science, Charles University, Albertov 6, Prague 12843, Czech Republic

4. Department of Pediatrics I, Medical University Innsbruck, Innrain 66, Innsbruck 6020, Austria

5. Department of Pediatrics II, Medical University Innsbruck, Innrain 66, Innsbruck 6020, Austria

Funder

Austrian Science Fund

Grantov? Agentura Cesk? Republiky

Akademie Ved Cesk? Republiky

Univerzita Karlova v Praze

Grantov? Agentura, Univerzita Karlova

Dr. Johannes und Hertha Tuba Stiftung

Publisher

American Chemical Society (ACS)