Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques
Author:
Affiliation:
1. School of Biological Sciences, University of Edinburgh, The King’s Buildings, Max Born Crescent, CH Waddington Building, Edinburgh, Scotland EH9 3BF, U.K.
Funder
Medical Research Council
Scottish Universities Life Sciences Alliance
European Community?s 7th Framework Program
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.7b02091
Reference35 articles.
1. Innovation in the pharmaceutical industry: New estimates of R&D costs
2. An analysis of the attrition of drug candidates from four major pharmaceutical companies
3. Drug repurposing from the perspective of pharmaceutical companies
4. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
5. Unlicensed and off label drug use in neonates Commentary
Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A Novel Confocal Scanning Protein–Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Interaction between the E2 Ubiquitin-Conjugating Enzyme CDC34A and Ubiquitin;Bioconjugate Chemistry;2024-08-21
2. Tryptophan metabolism in health and disease;Cell Metabolism;2023-08
3. Therapeutic potential of targeting kynurenine pathway in neurodegenerative diseases;European Journal of Medicinal Chemistry;2023-05
4. Acute administration of ibuprofen increases serum concentration of the neuroprotective kynurenine pathway metabolite, kynurenic acid: a pilot randomized, placebo-controlled, crossover study;Psychopharmacology;2022-10-22
5. Kynurenine‐3‐monooxygenase (KMO): From its biological functions to therapeutic effect in diseases progression;Journal of Cellular Physiology;2022-09-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3