Dissection of the Active Ingredients and Potential Mechanism of Han-Shi-Yu-Fei-Decoction in Treating COVID-19 Based on In Vivo Substances Profiling and Clinical Symptom-Guided Network Pharmacology

Author:

Jiao Guangyang1ORCID,Fan Xiangcheng23ORCID,Wang Yejian4,Weng Nan25,Ouyang Luolan6,Wang Haoqian6,Pan Sihan6,Huang Doudou1,Han Jun7,Zhang Feng234,Chen Wansheng123ORCID

Affiliation:

1. Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

2. Department of Pharmacy, Changzheng Hospital, (Second Military Medical University), Naval Medical University, Shanghai 200003, China

3. Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai 200433, China

4. Department of Pharmacology, Anhui University of Chinese Medicine, Hefei 230012, Anhui, China

5. School of Traditional Chinese Material, Shenyang Pharmaceutical University, Shenyang 11001, China

6. School of Pharmacy, Shanghai University of Chinese Medicine, Shanghai 201203, China

7. Department of Gastroenterology, Changzheng Hospital, (Second Military Medical University), Naval Medical University, Shanghai 200003, China

Funder

National Natural Science Foundation of China

Shanghai Changzheng Hospital

Jin-Zi-Ta Talent projects

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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