Exploring Selectivity of Multikinase Inhibitors across the Human Kinome
Author:
Affiliation:
1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstr. 2, D-53113 Bonn, Germany
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.7b01960
Reference33 articles.
1. Protein kinases — the major drug targets of the twenty-first century?
2. Targeting the cancer kinome through polypharmacology
3. Kinase Drug Discovery
4. Targeting kinases: a new approach to treating inflammatory rheumatic diseases
5. New Frontiers in Kinases: Second Generation Inhibitors
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