Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate)-Reference-Cited by-同舟云学术

Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate)

Published:2018-10-19 Issue:10 Volume:3 Page:13647-13666
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Kobayashi Naotake^ORCID,Sato Norihito,Fujimura Yuko,Kihara Tsuyoshi¹,Sugita Katsuji,Takahashi Kouji²,Koike Katsumi,Sugawara Tamio,Tada Yukio,Nakai Hiroshi,Yoshikawa Takayoshi³

Affiliation:

1. Business Search & Evaluation, Shionogi & Co., Ltd., 3-1-8, Doshomachi, Chuo-ku, Osaka-shi, Osaka 541-0045, Japan

2. DMPK Services, Shionogi Techno Advance Research Co., Ltd., 3-1-1, Futaba-cho, Toyonaka-shi, Osaka 561-0825, Japan

3. Pharmacovigilance Japan, Allergan Japan K.K., 4-20-3-35, Ebisu, Shibuya-ku, Tokyo 150-6035, Japan

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.8b01481

Reference93 articles.

1. The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide