Synthesis, Anticancer Activity, and <i>In Silico</i> Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer-Reference-Cited by-同舟云学术

Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer

Published:2024-02-14 Issue:8 Volume:9 Page:9547-9563
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Abbade Yemna¹²,Kisla Mehmet Murat¹²^ORCID,Hassan Mohammed Al-Kassim¹²³^ORCID,Celik Ismail⁴^ORCID,Dogan Tugba Somay⁵^ORCID,Mutlu Pelin⁶,Ates-Alagoz Zeynep¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey

2. Graduate School of Health Sciences, Ankara University, 06110 Ankara, Turkey

3. Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Bayero University, P.M.B 3011 Kano, Nigeria

4. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey

5. Central Laboratory, Molecular Biology and Biotechnology R&D Center, Middle East Technical University, 06800 Ankara, Turkey

6. Department of Biotechnology, Biotechnology Institute, Ankara University, 06135 Ankara, Turkey

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c09411

Reference70 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

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4. B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy

5. Elevated Expression of the Apoptotic Regulator Mcl-1 at the Time of Leukemic Relapse

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