Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease-Reference-Cited by-同舟云学术

Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease

Published:2020-06-09 Issue:24 Volume:5 Page:14750-14758
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Holshouser Steven¹,Cafiero Rebecca¹,Robinson Mayra¹,Kirkpatrick Joy¹,Casero Robert A.²,Hyacinth Hyacinth I.³,Woster Patrick M.¹^ORCID

Affiliation:

1. Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, 70 President St., Charleston, South Carolina 29414, United States

2. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 1650 Orleans St. Room 551, Baltimore, Maryland 21287, United States

3. Department of Pediatrics, School of Medicine, Emory University, 2015 Uppergate Dr., Atlanta, Georgia 30322, United States

Funder

Center for Scientific Review

Doris Duke Charitable Foundation

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.0c01585

Reference59 articles.

1. Histone lysine demethylases as targets for anticancer therapy

2. Translating the Histone Code

3. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

4. A decade of exploring the cancer epigenome — biological and translational implications

5. Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

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