New Approach to Drug Discovery of a Safe Mitochondrial Uncoupler: OPC-163493

Author:

Okamoto Takashi1,Shimada Takahiro2,Matsumura Chiharu3,Minoshima Hitomi4,Ban Takashi5,Itotani Motohiro6,Shinohara Toshio3,Fujita Shigekazu7,Matsuda Satoshi8,Sato Seiji3ORCID,Kanemoto Naohide1

Affiliation:

1. Department of Lead Discovery Research, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

2. Department of Drug Metabolism and Pharmacokinetics, Nonclinical Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

3. Medicinal Chemistry Research Laboratories, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

4. Pharmaceutical Planning Group, Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan

5. Department of Renal and Cardiovascular Research, New Drug Research Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

6. Quality Assurance Section (Tokushima Wajiki Factory), Quality Assurance Department, Headquarters for Product Safety and Quality Assurance, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

7. Human Resources Department, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

8. Administration Department, Diagnostic Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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