Enantioselective Total Synthesis of (−)-Candelalide A, a Novel Blocker of the Voltage-Gated Potassium Channel Kv1.3 for an Immunosuppressive Agent-Reference-Cited by-同舟云学术

Enantioselective Total Synthesis of (−)-Candelalide A, a Novel Blocker of the Voltage-Gated Potassium Channel Kv1.3 for an Immunosuppressive Agent

Published:2005-07-27 Issue:17 Volume:7 Page:3745-3748
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Watanabe Kazuhiro¹,Iwasaki Katsuhiko¹,Abe Toshiaki¹,Inoue Munenori¹,Ohkubo Kôichi¹,Suzuki Takeyuki¹,Katoh Tadashi¹

Affiliation:

1. Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan, Department of Electronic Chemistry, Tokyo Institute of Technology, Nagatsuta, Yokohama 226-8502, Japan, and Sagami Chemical Research Center, 2743-1 Hayakawa, Ayase, Kanagawa 252-1193, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol051398c

Reference14 articles.

1. Candelalides A−C: Novel Diterpenoid Pyrones from Fermentations of Sesquicillium candelabrum as Blockers of the Voltage-Gated Potassium Channel Kv1.3

2. Benzamide derivatives as blockers of Kv1.3 ion channel

3. Identification of a New Class of Inhibitors of the Voltage-Gated Potassium Channel, Kv1.3, with Immunosuppressant Properties

4. Terminally Alkylated Polyamine Analogues as Chemotherapeutic Agents

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