1. Kobe Pharmaceutical University, 4-19-1 Motoyamakita, Higashinada-ku, Kobe-shi 658-8558, Japan, Department of Biochemistry and Molecular Biology, Kyoto Prefectural University of Medicine, Kawaramachi-dori, Kamigyo-ku, Kyoto 602-0841, Japan, and Yokohama College of Pharmacy, 601 Matanocyo, Hodogayaku, Yokohama-shi 245-0066, Japan