Affiliation:
1. Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand
2. Pharmaceutical Biopolymer Group (PBiG), Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand
3. Faculty of Pharmacy, Siam University, Bangkok 10160, Thailand
Abstract
The present review explores the growing interest in the techniques employed for extracting natural products. It emphasizes the limitations of conventional extraction methods and introduces superior non-conventional alternatives, particularly ultrasound-assisted extraction. Characterization and quantification of bioactive constituents through chromatography coupled with spectroscopy are recommended, while the importance of method development and validation for biomarker quantification is underscored. At present, electrospun fibers provide a versatile platform for incorporating bioactive extracts and have extensive potential in diverse fields due to their unique structural and functional characteristics. Thus, the review also highlights the fabrication of electrospun fibers containing bioactive extracts. The preparation of biologically active extracts under optimal conditions, including the selection of safe solvents and cost-effective equipment, holds promising potential in the pharmaceutical, food, and cosmetic industries. Integration of experimental design into extraction procedures and formulation development is essential for the efficient production of health products. The review explores potential applications of encapsulating natural product extracts in electrospun fibers, such as wound healing, antibacterial activity, and antioxidant properties, while acknowledging the need for further exploration and optimization in this field. The findings discussed in this review are anticipated to serve as a valuable resource for the processing industry, enabling the utilization of affordable and environmentally friendly, natural, and raw materials.
Funder
Silpakorn University under the Postdoctoral fellowship
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference206 articles.
1. The Key Drivers of the Pharmacological Actions of Medicinal Plants;Philip;Herbal Medicine,2018
2. Fomo, G., Madzimbamuto, T.N., and Ojumu, T.V. (2020). Applications of nonconventional green extraction technologies in process industries: Challenges, limitations and perspectives. Sustainability, 12.
3. Ultrasound assisted extraction (UAE) of bioactive compounds from fruit and vegetable processing by-products: A review;Kumar;Ultrason. Sonochem.,2021
4. A new approach for process development of plant-based extraction processes;Kassing;Chem. Eng. Technol.,2010
5. Use of experimental design in the pharmaceutical industry;J. Pharm. Biomed. Anal.,1991
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献