Discovery of 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a Potent and Selective Inhibitor of Protein Kinase C Isotypes-Reference-Cited by-同舟云学术

Discovery of 3-(1H-Indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a Potent and Selective Inhibitor of Protein Kinase C Isotypes

Published:2009-09-18 Issue:20 Volume:52 Page:6193-6196
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wagner Jürgen¹,von Matt Peter¹,Sedrani Richard¹,Albert Rainer¹,Cooke Nigel¹,Ehrhardt Claus¹,Geiser Martin¹,Rummel Gabriele¹,Stark Wilhelm¹,Strauss Andre¹,Cowan-Jacob Sandra W.¹,Beerli Christian¹,Weckbecker Gisbert¹,Evenou Jean-Pierre¹,Zenke Gerhard¹,Cottens Sylvain¹

Affiliation:

1. Novartis Institutes for BioMedical Research, Basel CH-4002, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901108b

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5. Albert, R.; Cooke, N. G.; Cottens, S.; Ehrhardt, C.; Evenou, J.P.; Sedrani, R.; von Matt, P.; Wagner, J.; Zenke, G.Indolylmaleimide Derivatives as Protein Kinase C Inhibitors. PCT Int. Appl. WO 2002/038561 A1, 2002.

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