Synthesis and Biological Activity of Flurbiprofen Analogues as Selective Inhibitors of β-Amyloid1-42 Secretion-Reference-Cited by-同舟云学术

Synthesis and Biological Activity of Flurbiprofen Analogues as Selective Inhibitors of β-Amyloid1-42 Secretion

Published:2005-08-06 Issue:18 Volume:48 Page:5705-5720
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Peretto Ilaria¹,Radaelli Stefano¹,Parini Carlo¹,Zandi Michele¹,Raveglia Luca F.¹,Dondio Giulio¹,Fontanella Laura¹,Misiano Paola¹,Bigogno Chiara¹,Rizzi Andrea¹,Riccardi Benedetta¹,Biscaioli Marcello¹,Marchetti Silvia¹,Puccini Paola¹,Catinella Silvia¹,Rondelli Ivano¹,Cenacchi Valentina¹,Bolzoni Pier Tonino¹,Caruso Paola¹,Villetti Gino¹,Facchinetti Fabrizio¹,Del Giudice Elda¹,Moretto Nadia¹,Imbimbo Bruno P.¹

Affiliation:

1. Research &Development, Chiesi Farmaceutici S.p.A., Via Palermo 26/A, 43100 Parma, Italy, NiKem Research, Via Zambeletti 25, 20021 Baranzate, Milan, Italy, Neurobiology Unit, Research & Innovation, Via Svizzera 16, 35127 Padua, Italy, and Department of Biochemistry and Molecular Biology, University of Parma, Parco Area delle Scienze 23/A, 43100 Parma, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0502541

Reference38 articles.

1. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies

2. Nonsteroidal Anti-inflammatory Drugs and Alzheimer Disease

3. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

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