Cyclopropanation of Aryl and Styryl Acetonitriles With Selenium‐Based Dielectrophiles-Reference-Cited by-同舟云学术

Cyclopropanation of Aryl and Styryl Acetonitriles With Selenium‐Based Dielectrophiles

Published:2024-05-17 Issue:21 Volume:27 Page:
ISSN:1434-193X
Container-title:European Journal of Organic Chemistry
language:en
Short-container-title:Eur J Org Chem

Author:

Coelho Dias Italo Franco¹,Allegrini Giulia¹,Wielgus Ewelina²,Drabowicz Józef²³,Lenardão Eder João⁴,Bagnoli Luana¹,Santi Claudio¹,Marini Francesca¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences Group of Catalysis Synthesis and Organic Green Chemistry University of Perugia Via del Liceo 1 06123 Perugia Italy

2. Centre of Molecular and Macromolecular Studies Polish Academy of Sciences Sienkiewicza 112 90-363 Lodz Poland

3. Institute of Chemistry Jan Dlugosz University in Czestochowa Armii Krajowej Ave. 13/15 42-200 Czestochowa Poland

4. Laboratório de Síntese Orgânica Limpa (LASOL) Centro de Ciências Químicas Farmacêuticas e de Alimentos (CCQFA) Universidade Federal de Pelotas (UFPel) P.O. Box 354 96010-900 Pelotas, RS Brazil).

Abstract

AbstractEfficient cyclopropanation reactions of aryl or styrylacetonitriles with vinyl selenones under mild conditions were described. By this approach, synthetically challenging 1‐vinylcyclopropane‐1‐carbonitriles were accessible in good yields. This methodology features the advantage of operational simplicity, broad substrate scope, good functional group tolerance, transition‐metal‐free conditions, mild temperature, and a high level of regio‐ and diastereo‐control.

Funder

Università degli Studi di Perugia

Publisher

Wiley

Reference79 articles.

1. For recent reviews see:

2. A New Golden Age for Donor-Acceptor Cyclopropanes

3. Donor‐Acceptor Cyclopropanes in the Synthesis of Carbocycles

4. Recent advances in ring-opening of donor acceptor cyclopropanes using C-nucleophiles