The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity

Author:

Zhang Dapeng1ORCID,Atochina-Vasserman Elena N.2ORCID,Lu Juncheng1,Maurya Devendra S.1ORCID,Xiao Qi1ORCID,Liu Matthew1ORCID,Adamson Jasper1,Ona Nathan2,Reagan Erin K.2ORCID,Ni Houping2,Weissman Drew2ORCID,Percec Virgil1ORCID

Affiliation:

1. Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States

2. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

Division of Chemistry

University of Pennsylvania

Alexander von Humboldt-Stiftung

Division of Materials Research

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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