Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in Neisseria gonorrhoeae: Role of Epistatic Mutations-Reference-Cited by-同舟云学术

Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in Neisseria gonorrhoeae: Role of Epistatic Mutations

Published:2010-08-25 Issue:37 Volume:49 Page:8062-8070
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Tomberg Joshua¹,Unemo Magnus²,Davies Christopher³,Nicholas Robert A.¹

Affiliation:

1. Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599-7365

2. National Reference Laboratory for Pathogenic Neisseria, Department of Laboratory Medicine, Clinical Microbiology, Örebro University Hospital, Örebro, Sweden

3. Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina 29425

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi101167x

Reference35 articles.

1. Centers for Disease Control and Prevention (2009) Sexually Transmitted Disease Surveillance 2007 Supplement, Gonococcal Isolate Surveillance Project (GISP) Annual Report 2007.Centers for Disease Control and Prevention,Atlanta.

2. Mosaic-Like Structure of Penicillin-Binding Protein 2 Gene ( penA ) in Clinical Isolates of Neisseria gonorrhoeae with Reduced Susceptibility to Cefixime

3. Meeting the public health challenge of multidrug- and extensively drug-resistantNeisseria gonorrhoeae

4. Ceftibuten Resistance and Treatment Failure of Neisseria gonorrhoeae Infection

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