Design, Synthesis, and Biological Evaluation of Antibody−Drug Conjugates Comprised of Potent Camptothecin Analogues-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Antibody−Drug Conjugates Comprised of Potent Camptothecin Analogues

Published:2009-05-26 Issue:6 Volume:20 Page:1242-1250
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Burke Patrick J.¹,Senter Peter D.¹,Meyer David W.¹,Miyamoto Jamie B.¹,Anderson Martha¹,Toki Brian E.¹,Manikumar Govindarajan¹,Wani Mansukh C.¹,Kroll David J.¹,Jeffrey Scott C.¹

Affiliation:

1. Seattle Genetics, Inc., 21823 30th Drive SE, Bothell, Washington 98021, Research Triangle Institute, Natural Products Laboratory, Research Triangle Park, North Carolina 27709, and North Carolina Central University, Pharmaceutical Sciences, BRITE, Durham, North Carolina 27707

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc9001097

Reference37 articles.

1. Antibody-Drug Conjugates for Cancer Therapy

2. Targeted Cancer Therapy: Conferring Specificity to Cytotoxic Drugs

3. Arming antibodies: prospects and challenges for immunoconjugates

4. Development of potent monoclonal antibody auristatin conjugates for cancer therapy

5. cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity

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