The Nucleotide Sequence, DNA Damage Location, and Protein Stoichiometry Influence the Base Excision Repair Outcome at CAG/CTG Repeats

Author:

Goula Agathi-Vasiliki1,Pearson Christopher E.2,Della Maria Julie3,Trottier Yvon1,Tomkinson Alan E.3,Wilson David M.4,Merienne Karine1

Affiliation:

1. Department of Neurogenetics and Translational Medicine, Institute of Genetics and Molecular and Cellular Biology (IGBMC), UMR 7104-CNRS/INSERM/UdS, Illkirch, France

2. Genetics and Genome Biology, The Hospital for Sick Children, TMDT Building, 101 College Street, 15th Floor, Room 15-312, East Tower, Toronto, ON, M5G 1L7 Canada, and Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada

3. Department of Radiation Oncology and Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States

4. Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, United States

Funder

Canadian Institutes of Health Research

National Institutes of Health

National Institute on Aging

Muscular Dystrophy Association

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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