Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)-Reference-Cited by-同舟云学术

Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)

Published:2010-04-21 Issue:9 Volume:53 Page:3618-3625
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Haynes Nancy-Ellen¹,Corbett Wendy L.¹,Bizzarro Fred T.¹,Guertin Kevin R.¹,Hilliard Darryl W.¹,Holland George W.¹,Kester Robert F.¹,Mahaney Paige E.¹,Qi Lida¹,Spence Cheryl L.²,Tengi John¹,Dvorozniak Mark T.²,Railkar Aruna³,Matschinsky Franz M.⁴,Grippo Joseph F.²,Grimsby Joseph²,Sarabu Ramakanth¹

Affiliation:

1. Departments of Discovery Chemistry

2. Metabolic and Vascular Diseases

3. Non-Clinical Drug Safety, and Discovery Technologies, Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, New Jersey 07110

4. Department of Biochemistry and Diabetes Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100039a

Reference16 articles.