Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening
Author:
Affiliation:
1. Center for Advanced Biotechnology and Medicine, ‡Department of Chemistry and Chemical Biology, and §Department of Medicinal Chemistry, Rutgers University, Piscataway, New Jersey, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm301271j
Reference42 articles.
1. Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition
2. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): Past, Present, and Future
3. HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism
4. Indolopyridones Inhibit Human Immunodeficiency Virus Reverse Transcriptase with a Novel Mechanism of Action
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