Structure−Activity Relationships of 1-Alkyl-5-(3,4-dichlorophenyl)- 5-{2-[(3-substituted)-1-azetidinyl]ethyl}-2-piperidones. 1. Selective Antagonists of the Neurokinin-2 Receptor-Reference-Cited by-同舟云学术

Structure−Activity Relationships of 1-Alkyl-5-(3,4-dichlorophenyl)- 5-{2-[(3-substituted)-1-azetidinyl]ethyl}-2-piperidones. 1. Selective Antagonists of the Neurokinin-2 Receptor

Published:2002-10-26 Issue:24 Volume:45 Page:5365-5377
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

MacKenzie A. Roderick¹,Marchington Allan P.¹,Middleton Donald S.¹,Newman Sandra D.¹,Jones Barry C.¹

Affiliation:

1. Departments of Discovery Chemistry and Drug Metabolism, Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0209331

Reference32 articles.

1. Molecular cloning, structural characterization and functional expression of the human substance P receptor

2. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues

3. The primary structure and gene organization of human substance P and neuromedin K receptors

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