Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties-Reference-Cited by-同舟云学术

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Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties

Published:2014-08-06 Issue:10 Volume:5 Page:1162-1166
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Zhang Yanmei¹,Tortorella Micky D.¹,Wang Yican¹,Liu Jianqi¹,Tu Zhengchao¹,Liu Xiaorong¹,Bai Yang¹,Wen Dingsheng¹,Lu Xin¹,Lu Yongzhi¹,Talley John J.²³

Affiliation:

1. Drug Discovery Pipeline, Guangzhou Institutes of Biomedicine and Health, Science City, Guangzhou 510530, P. R. China

2. Department of Chemistry, St. Louis University, St. Louis, Missouri 63108, United States

3. Euclises Pharmaceuticals, St. Louis, Missouri 63108, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml500299q

Reference27 articles.

1. The pyrrole moiety as a template for COX-1/COX-2 inhibitors

2. Le traitement de la polyarthrite rhumatoïde. Évolution des idées et des stratégies

3. Update on Cyclooxygenase-2 Inhibitors

4. Physiological Regulation of Prostaglandins in the Kidney

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