The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues-Reference-Cited by-同舟云学术

The Squalestatins: Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues

Published:1996-01-01 Issue:7 Volume:39 Page:1413-1422
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Procopiou Panayiotis A.¹,Cox Brian¹,Kirk Barrie E.¹,Lester Michael G.¹,McCarthy Alun D.¹,Sareen Meenu¹,Sharratt Peter J.¹,Snowden Michael A.¹,Spooner Stephen J.¹,Watson Nigel S.¹,Widdowson Julia¹

Affiliation:

1. Departments of Medicinal Chemistry and Molecular Science, Glaxo Wellcome Research and Development, Medicines Research Center, Gunnels Wood Road, Stevenage, SG1 2NY, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950893j

Reference27 articles.

1. The squalestatings, novel inhibitors of squalene synthase produced by a species of Phoma. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.

2. The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. V. Minor metabolites.

3. The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. II. Structure elucidation.

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